[aartur]

I think the most popular is https://pypi.python.org/pypi/Baker/. And I like automatic introspection of callables very much - no more argument parsing, just a decorator under a function. Sure this is not suitable for polished CLI interfaces, but my use cases are almost only in-house scripts for internal usage.

[ot]

+1 for Baker, it is the first script I import in my git repo when writing a python tool.

A big plus is that it is a single file (baker.py) with no dependencies, which is very useful when I have to use my scripts on machines I don't have root access on. (I know about virtualenv, but it is definitely overkill for most of the things I do)