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by driverdan 4797 days ago
It depends on your stack. I built a PHP app that could handle 100+ req/s per server with only app config data cached and a reasonable level of MySQL table cache.

For an MVC framework like Rails, however, cache is going to be needed much earlier. I'd launch without it but once I got some traction it's one of the first things I'd work on. Since Rails has built in cache support it's pretty easy to setup some basic caching.