[RVijay007]

Just to clarify, this is not whole organ decellularization. The brain tissue, with it's neurons, glia, ECM, are left all in tact, along with their proteins, mRNA, etc.

Now, instead of having to slice the brain into micrometer slices just to understand architecture at a localized level, you can understand the architecture of the whole brain's network down to the cellular level, as well as do both immunohistochemistry and in-situ hybridization to probe what kind of proteins and molecular markers are present throughout the brain. This is nothing short of a revolution in experimental technique not only for neuroscience, but all of pathology.