Nope. Since no one can ever satisfactory answer the question of the 'real' amount of BTC in circulation, this will only serve as a factor of uncertainty. Lost bitcoins affect nothing, FOUND bitcoins can affect everything.
So, MV=PQ and all that. Lost bitcoins are functionally identical to any other bitcoins that aren't being spent. Burning dollar bills does not move the price of the dollar in a different way than keeping them in your pocket.