[cageface]

Storyboards:

1. Interact poorly with version control.

2. Scale badly with a lot of VCs.

3. Segues are untyped and are inadequate to express complex navigation schemes.

AutoLayout:

1. Excessively verbose normal syntax and excessively limited and cryptic and untyped shorthand syntax.

2. IB tools are woefully inadequate for editing.

3. Small adjustments to complex layouts in IB completely scramble the constraints.

4. Does nothing to make the 95% use case of nested grid layouts explicit and simple.

[sjtgraham]

2. Is the fundamental deal breaker. They're impossible to use in a multi-developer environment, because of the absolutely guaranteed merge conflicts at every turn.

[cageface]

I now have a one-VC per storyboard rule, which helps. I wouldn't use them all if I could design custom table/collection cells in xibs.