[Riley]

I have been using a single 30" monitor as my main display since 2005. I love it. Only problem is having to adjust whenever working on another system (also been using it with a standing desk since 2008).

I split the screen space up into conveniently sized tiles most of the time. Most often using only half the monitor width at most (like two 1280x1600 monitors side by side, but no bezel line in the middle). But occasionally using the full screen real estate for one program is really nice.