[tomh]

+1 for bioinformatics - adding to that are the issues surrounding the complexity of the data (look up HL7 or CDISC to see how complex) and also the legal standards and ramifications (HIPPA, 21 CFR Part 11) of working with clinical research.

In short, getting domain knowledge in the above are essential to solve the tough problems at the big-pharma or national-bio-labs level.

(PS to the other poster looking for bioinformatics programs: I suggest you look in Boston - Tufts, MIT, Harvard etc)