Probably not, C-F bonds are extremely stable, so perfluoro compounds are biologically inert. The datasheet says they made some animal inhale 10% (!) Novec gas for 4 hours without effect.
It has half-life of 5 days in the atmosphere, so it's not that stable. According to the MSDS it and degrades both when exposed to UV and at high temperature (like those present in a structural fire) into hydrogen fluoride gas, which becomes hydrofluoric acid upon contact with moisture (including biological tissue).
Also you're supposed to dike the area if a major spill occurs, but I'm pretty sure that's just MSDS boilerplate.