[pasbesoin]

A few years ago, I saw a news article about a small Canadian study (out of Alberta, I think; maybe the University at Edmonton) that found nicotine to be as effective as prescription medications in mediating AD(H)D symptoms. I've seen other items online emphasizing its effect on concentration.

I'm having trouble googling up a reference, but I did find this:

http://www.accessibility.com.au/news/adhd-appears-to-increas...

"We've already shown that nicotine-based medications can treat ADHD symptoms"

[chris11]

Wikipedia did mention that nicotine has several psychoactive effects. It reduces stress. And amazingly enough, it can work as both a sedative and a stimulant. http://en.wikipedia.org/wiki/Nicotine#Psychoactive_effects

[furburger]

yeah like gangrene cures cancer

[chris11]

Or like radiation cures cancer. Radiation treatment is basically just controlled radiation poisoning. A lot of the side effects are the same. Nothing is totally beneficial, or totally detrimental.

[furburger]

smoking is partially beneficial? i'm interested to see the hacker response to forty years of medical research to the contrary

[chris11]

I'm not saying that it's not horribly detrimental. I'm just saying that it has some small benefits. Nicotine can cause weight loss, act as a stimulant, and reduce stress. Though all of those benefits can be gotten a lot safer ways.

Nature ran an article about how a patent was keeping an arsenic based cancer drug out of reach of patients.

Nothing is all bad.

http://www.nature.com/nm/journal/v13/n9/full/nm0907-1005.htm... (subscription required)..

[scott_s]

As you pointed out, nicotine is a stimulant; I doubt it's the nicotine that reduces stress. What's probably happening is that when a smoker lights up, their brain releases dopamine because they're finally getting what they're addicted to.

In the same manner, a cup of coffee can relax someone if they're a caffeine addict.

[colins_pride]

One of the things I've struggled with is figuring out if I'm addicted to something ..

One way to judge is to look for withdrawal symptoms, but this requires changing my behavior to test ..

So the idea is that if something that stimulates most people, and used to stimulate me, now relaxes me, I've become dependent on it ..

Very intuitive

[chris11]

That is a good point. When addicts use drugs their stress is reduced. But nicotine is unique in that its profile depends on the dose.

When smokers want to have more concentration, they take short and quick puffs. This gets a low level of nicotine in the blood. At a low dose, nicotine increases norepinephrine and dopamine. So it acts like a stimulant.

When smokers want to relax, they take long and deep puffs. This increases the dose of nicotine. And at high doses, it affects serotonin and opiate levels in the brain and acts like a sedative.

http://en.wikipedia.org/wiki/Nicotine#Psychoactive_effects

[kingkongrevenge]

I guess you could form a complicated theory like that. Or you could try smoking a cigarette and notice that it relaxes and focuses you.

[kingkongrevenge]

> smoking is partially beneficial?

Yes, actually. Protective against Alzheimers and Parkinsons.

Inhaled tobacco smoke actually has MAO inhibitors in it, which is beneficial for certain people.

[likpok]

The big issue with smoking is not the nicotine. It is the tar/additives that make their way to your lungs and give you cancer.

[furburger]

actually one common form of nicotine is in fact a deadly poison

[Radix]

Why would anyone downvote this guy. It's sourced.

http://en.wikipedia.org/wiki/Nicotine#Toxicology

[pasbesoin]

I was responding specifically to nikblack's comment about finding it more effective than caffeine when hacking. I didn't mean to imply it's all puppies and daisies.

Amongst other things, nicotine's a vasoconstrictor. Long term exposure may not be the best thing for one's cardiovascular system, even leaving out the tar, volatiles, and plutonium that come with tobacco smoke.

Then there's the whole dance it performs with neurotransmitters and multiple addictive centers in the brain. I recall some researchers speculating that it may be so addictive at least in part because it activates multiple centers associated with addiction, whereas most drugs only activate one or another of those centers.