[dfc]

If you just need to do crypto in python use keyczar[1] or pynacl[2], and keyczar is probably the best bet.

But if you need to do gpg compatible crypto use the python wrapper for gpgme:

  pygpgme exposes the gpgme library to Python. The product was started by
  James Henstridge. Beside Python2 it supports Python 3 since v0.3 (March
  2012). The wrapping is done using python's C interface directly without
  using a generator tool like SWIG.[3]

[1] http://www.keyczar.org

[2] https://github.com/seanlynch/pynacl

[3] http://pypi.python.org/pypi/pygpgme