Page weight is an issue generally, but particularly for people on mobile where there are often relatively low bandwidth caps before the insane fees kick in.
Page "girth", the number of different parts of a page that need loading via separate requests, is often a more significant issue for performance, again particularly on mobile devices but this time because wireless connections tend to be less reliable and even a modest increase in dropped packets can really hit your effective page load time.
400 round trips * 500ms latency is 3 min 20 seconds. This took 20 minutes to load 1 megabyte.