yep. see http://www.riverbankcomputing.com/news/pyqt-496. the pyqt bindings are supported by riverbank, which offers commercial licenses, so they have every incentive to keep it up to date.
There is a book out there called "Rapid GUI Programming with Python and Qt The Definitive Guide to PyQt Programming
by Mark Summerfield" Code downloadable here:
http://www.qtrac.eu/pyqtbook.html
In all the code in that book you can just substitute "import PySide" for "import PyQt4" and pretty much everything works. In addition, if you install Qt4Assistant you will have a searchable tool for all classes and documentation.