[alexgieg]

Try knowing some in real life. I know dozens, and it's really hard not to think of them as psychologically being of the opposite gender. This tracks with the fact that neuroimaging of trans brains shows that the areas in which male and female brains differ are either of the opposite gender or have in-between values.

[cubefox]

> Try knowing some in real life. I know dozens, and it's really hard not to think of them as psychologically being of the opposite gender.

I'm not sure what you mean with "opposite gender" (given that "gender" is now often no longer considered a synonym for "sex"), but I can tell you that all the MtF people I knew from college registered to me simply as men trying to act like women.