Frankly, such paradigm shifts are almost impossible for humans as well. If a mathematician proposes a truly radical paradigm shift, they're either a once-in-a-decade genius or a crackpot.
It is quite typical that once in a decade genius is treated like a crackpot... (what was the name of the Austrian doctor that suggested washing you hands before surgery?)
... of course, the number of crackpots is overwhelming
... of course, the number of crackpots is overwhelming