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by robbiep 4933 days ago
This appears to build on similar work using modified T-cells against Chronic Lymphocytic Leukemia from back in 2005 [1]

Fascinating stuff and it seems like all of the leukemias may fall to a strategy like this one.

One of the advantages of the use of this treatment in CLL was that patients were 'immunised' against recurrence of the cancer in the future. It seems that it is not yet known if this is the case for the treatment discussed here.

Nice to see that work is progressing by leaps and bounds in this area.

[1] http://www.nejm.org/doi/full/10.1056/NEJMoa1103849

2 comments

I got the impression from Siddhartha Mukherjee's The Emperor of All Maladies: A Biography of Cancer that (aside from a few minor skin cancers) Leukemia has always been the easiest cancer to attack and study, since it shows up in the blood. But it's been a damn long road from early successes almost 70 years ago.
Thanks for the reference - as someone with CLL you can't imagine what went through my head when I read about this and wondered how transferable the treatment would be to other blood cancers.
I hope they hurry up and bring it to the mass market.. I really hope that it will be available for you to use.