Irrelevant to your point, but drug users dying is more often the result of a dealer cutting their supply with something dangerous than it is the result of purity.
No, not really as almost no one runs LLMs in confinement once they are released and the capability is a jailbreak away. Poor confinement is irrelevant, if I use your model to check the security of my code and it hacks into the company that makes libraries used inside of it it's a huge problem.