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by dubious2 11 days ago
What are the risks of testosterone therapy for normal aging? Testosterone therapy has various risks, including:

Worsening sleep apnea — a potentially serious sleep disorder in which breathing repeatedly stops and starts. Causing acne or other skin reactions. Stimulating noncancerous growth of the prostate (benign prostatic hyperplasia) and growth of existing prostate cancer. Enlarging breasts. Limiting sperm production or causing testicles to shrink. Stimulating too much red blood cell production, which contributes to the increased risk of forming a blood clot. A clot could break loose, travel through your bloodstream and lodge in your lungs, blocking blood flow (pulmonary embolism). Also, some research shows that testosterone therapy can increase your risk of heart disease. More research is needed. Dear leader knows best!

1 comments

For physiological level replacement, not a lot. But also, you don't get a whole lot of additional benefit for going over the lower end of the reference range, and people usually don't fall below that.
Isnt the issue that it happens quite a lot more since test levels on average dropped a ton? (in part due to various lifestyle choices which should be focused on first but arguably also due to various polutants)
I strongly suspect that most of the issues correlated with low testosterone are co-symptoms rather than caused by it. From my research, it doesn't seem like going much above the lower end of the T range carries much additional benefit, other than muscle mass, and testosterone replacement in people with merely low testosterone doesn't do as much good as people think it does.