[lonelyasacloud]

If it’s waste to be cleared then a plateau would be the default assumption. Degradation past a point suggests something else.

[DANmode]

That the medication is additional burden on already overwhelmed detoxification processes?

My best guess.

[lonelyasacloud]

It could be a burden. Another intriguing possibility is that the waste isn't waste, instead maybe something necessary to trigger or run some other form of protective process.