[mmooss]

Regarding the unintentional overdoses:

"There are two distinct clinical syndromes described in literature. One is the 'garden variety', wherein the patients ingested large amounts of acetaminophen with a suicidal intent .... The other pattern is seen in chronic alcoholics who ingest smaller amounts of acetaminophen in an attempt to relieve pain ...."

"The causes of chronic pain in the accidental overdose group were toothache, chronic backache, or headache."

https://link.springer.com/article/10.1186/cc1475

[ctoa]

Yes, and those alcoholics also exactly fit the multi-day accumulation pattern. These aren't people taking one day of Tylenol after a bender for a hangover. The pattern is people with an impaired ability to process acetaminophen (alcoholics) taking multiple days of doses they can't handle (their daily safe dose is about 1/2 of normal) for chronic pain (like chronic back pain).