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by dualvariable 20 days ago
> they're not sure if the vaccine will last in your system for more than 30 years

Vaccines don't really last in your system more than a few days (although some cells get dragged off to the lymph nodes and get harshly interrogated for longer than that). It is the T-cell and B-cell responses that are persistent for years.

> and that subsequent doses may be less effective

They should activate B cells that you already have and produce high-affinity mature antibodies.