[Panzerschrek]

Can I write a game using OpenGL in Lisp?

[nmdev]

Yes. Kandria [1] is a great example of someone doing exactly this. There's a bunch of information on the development here [2] and the code is open source [3].

[1] https://kandria.com/

[2] https://reader.tymoon.eu/article/413

[3] https://codeberg.org/shirakumo/kandria

[Panzerschrek]

Interesting. I didn't thought it's possible.