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by amingilani 24 days ago
...in mice.

> Therefore, this study examined the effects of late middle-aged (18-month-old) male and female C57BL6/J mice receiving two intranasal doses of hiPSC-NSC-EVs on neuroinflammaging in the hippocampus at 20.5 months of age.

https://isevjournals.onlinelibrary.wiley.com/doi/10.1002/jev...

3 comments

That PR piece was brutal to navigate. Undoubtedly punched up by AI, it took far too long to even understand what the treatment entailed.
To be fair though, I think we owe the mice a positive research outcome.
“Congratulations, you get improved brain function while we continue to run other experiments on you!”
You can now experience both physical pain and existential dread!
On the plus side, expect to see great works of literature authored by rodents.
“There will be cake!”
The link to the actual paper was appreciated. The context of whether findings will generalize outside of mouse models can depend a lot on specifics of the problem.