[milleramp]

"inhibition fails" reminded me of this passage from Fear and Loathing.

"Ah, devil ether. It makes you behave like the village drunkard in some early Irish novel... total loss of all basic motor skills. Blurred vision, no balance, numb tongue. The mind recoils in horror, unable to communicate with the spinal column."

[willy_k]

It’s worth noting that in neuro speak, inhibition does not necessarily correlate with what would appear to be a “dis/inhibited” person; it’s referring to a specific process where signals are blocked from propagating, and because the brain is made of a complex web of inter-modulatory loops, this can show up in unintuitive ways

e.g. signals from the default mode network getting in the way of task-oriented behavior, which can result in people appearing “inhibited” where in actuality they’re failing to inhibit irrelevant internal signals and (errant bottom-up) attention to them (this is the case in ADHD).

[taneq]

Think of it like a relay with a normally closed contact.