[catigula]

I’ve been taking high doses long term for over a decade and I don’t really have any substantial issues.

[derekja]

The primary concern is reduced stomach acid leading to nutrient deficiencies, particularly b12. There have been some long term studies correlating to dementia as a result. And some studies that have not found this. So the jury is still out, but keeping an eye on some nutritional markers is not a bad idea.

[dotcoma]

Good for you, but this mere fact does not mean it’s ideal.

Not a doctor, but I would at least try to look into this. Best of luck!