[justusthane]

No, they're very different. Using webkitdirectory="true" on an <input> element just allows you to select a directory to e.g. upload it to the server. It's a one-time operation.

This API returns a handle to the selected directory, giving the webpage ongoing read/write access to the directory.

You couldn't use the former to e.g. create a local-first notes app that stores its files on disk.