Multiple shotgun shells mounted inside of flying platform for final product. For prototyping it is regulatory nightmare in Germany though. That’s a trade-off reusability vs. hard hit. I took Rheinmetall’s calculation of 1000€ for single piece of their magic anti drone munition for business case.
I've also seen videos of drones equipped with shotguns shooting down drones, but those seem to mostly be smaller drones, not long range Shahed drones.
In either case, both are examples of re-usable interceptors, manned and unmanned.