The gap between reality and satire was apparently already very small back when the the show was written. The creator, Mike Judge (who also created Beavis & Butthead, and Idiocracy) had worked in Silicon Valley as a developer and based the show on what he saw. Apparently it was very popular with SV insiders precisely because it was so accurate.
Judge also consulted with various teams at places like Google; I worked with one of the guys who provided details that later showed up on the show (as well as many plushies). He didn't watch the show because "it hit too close to home"