n=1, tirzepatide puts my brain into "neutral," [1] I do not have strong feelings anymore on most anything not "fight or flight." Ego death via GLP-1 if you will. Probably has something to do with how it patches the reward center and its link to impulsive behavior in the prefrontal cortex [2].
It is kind of interesting the implications of "making you feel less hungry" in terms of a general insensitivity to the bodies own signalling mechanisms, vs just a hyper convenient targeted approach that only strikes the hunger portion of the dopamine-reward mechanism.
I wonder if you can do a simple experiment between glp and non glp users where you try and measure various biological response to giving someone say $20?
Going further I wonder if it affects other responses like pain response. How long might you keep your hand on a plate warming up? I seem to remember that sort of experimental setup in my undergrad days of signing up for every psychology department experiment under the sun for beer money.