Depends on whether LE is compelled to terminate service to BGP AS numbers hosted in U.S.-sanctioned countries, and whether LE continues operating out of the U.S..
It works like this. The US gov sends LE a nastygram saying they must terminate service to sanctioned entities. LE either does that or several people go to jail. The USgov doesn't care how it happens, as long as they can't find any evidence that any sanctioned entities are LE customers.