[jampekka]

My bet is on obesity.

"Overweight and obesity significantly increase colorectal cancer risk: a meta-analysis of 66 studies revealing a 25–57% elevation in risk" https://pmc.ncbi.nlm.nih.gov/articles/PMC12181496/

[red-iron-pine]

yeah HPV is definitely an angle, but there are easy fixes -- HPV vaccines work, as do condoms.

obesity is still a big driver and is a much harder fix. GLP-1s work but it's not one-and-done like a vaccine

[jampekka]

Saying condoms are an easy fix to STDs is a bit like saying eating less is an easy fix for obesity though.