[notafox]

- Independent set of extensions (independently configured) for each profile.

- Independent set of settings/about:config parameters.

You can't turn off, say, WebRTC completely for some profiles, while allowing it for other profiles.

Different history. I remember accidentally nuking history of a few years - that wasn't fun. Now, you reduce blast radius.

Proxy on/off or different proxies. Though, there's probably an extension that manages it on per-site basis.

Different userChrome.css, if you fancy that.

[akimbostrawman]

>I remember accidentally nuking history of a few years - that wasn't fun.

If you are on linux I can't recommend enough using a COW filesystem like btrfs and zfs with snapshots. I can't count the amount of times i have wiped or edited something by mistake and then restored it within seconds with it.