[dredmorbius]

Hand-foot syndrome, a/k/a chemotherapy-induced acral erythema, is a similar condition, though there may be another I'm confusing with.

<https://en.wikipedia.org/wiki/Chemotherapy-induced_acral_ery...>

I'd first run across this decades ago in the context of FDA drugs trials, in which adverse incidents were noted. My understanding at the time was that certain chemotherapies tended to interfere with skin regeneration, particularly in areas subject to high wearing (hands, feet, elbows), or rapid replacement (particularly mucous membranes, lips and mouth especially).

Not all chemotherapies are brutal, but some can be quite fiendish, and quality of life is a legitimate consideration when considering whether to proceed with treatment. Informed decisionmaking and consent in a context where expertise is rare and clinicians don't directly experience the adverse effects is difficult at best.