[pcthrowaway]

> with prescription and illicit opioids responsible for 500,000 of those deaths"

So... it's not saying 500K deaths are from prescription drugs, it's saying 500K deaths are from opioids (some of which were prescription)

Also, in the chart you mentioned, it's not clear if the opioid deaths were from legally produced prescription opioids. Certainly fentanyl is one of the biggest killers, and fentanyl is used in medical settings, but the fentanyl killing people is usually not from legal drug manufacturers.