[jona-f]

It's a pretty bad drug, I can see only disadvantages over plain amphetamine.

If amphetamine isn't strong enough, you already have a serious problem.

I'm not saying that criminalization is the right way, just that I don't see a responsible recreational/performance use for methamphetamine. It's too strong and too toxic. The regulation should permit only use for addiction management imho.

Also, the long history is not exactly in its favor, given how the Nazis extensively used it and Hitler was probably a serious meth-junkie.

[jampekka]

> It's a pretty bad drug, I can see only disadvantages over plain amphetamine.

The main "advantage" is probably the smoking RoA of methamphetamine. The RoA difference is likely a larger factor in methamphetamine vs plain amphetamine effects than the pharmacology of the molecule.

[keepamovin]

Not saying the risk profiles are the same, but some of the perception of different danger might be psychosocial normative informed by the differing criminalization. Plausible at least no? Important to keep that in mind.

[nswango]

Does history record whether Hitler was using the good ol' giggles-and-joy pseudoephedrine meth or the evil psychosis-inducing P2P biker meth?

[jona-f]

I think they were using the racemate. But your "giggles-and-joy" framing of meth is bullshit. Not sleeping for 3 days is psychosis-inducing no matter how you achieve that and methamphetamine is much more neurotoxic than amphetamine no matter which enantiomere.