[lo_zamoyski]

"For it seems that the struggle, the uncertainty, the incompleteness, they all might be the central theme of humanism, perhaps even its very essence."

Uncertainty and incompleteness are only meaningful in relation to certainty and completeness, and these point at desire. We desire food to complete us nutritionally, at least for a time. When we desire to know something, our minds come to rest - relatively speaking - when we arrive at that knowledge.

The questions then become: what is lacking to make something uncertain? What is lacking to make something incomplete? So, while these defects may be unavoidable (at least in his life), then the question one should be asking is what does the apparent insurmountably of this condition entail? What is the desire in question that isn't being satisfied?