[totalperspectiv]

"requires" is a strong word, but I implemented an alignment kernel that can do alignments on the GPU.

Overall I think there is going to be a lot of "old" gpu compute hanging around, and now that writing kernels is a lot easier than it has been, we might as well try and see what algorithms we can get working there.

I originally picked up Mojo for the SIMD, not for the GPU kernels. The SIMD usability in Mojo is outstanding.

Paper on the tool I wrote: https://doi.org/10.1093/bioadv/vbaf292

[samuell]

Very cool!

I have been pretty hopeful about Mojo as I find many of the modern compiled languages these days requires an surprisingly excessive amount of ceremony just to open a file and read it line by line. At least this is the case with Go, as I've written about [1].

If Mojo is providing any kind of python like experience in this matter, I will be all into it again (it lacked these features when I last tried).

[1] https://livesys.se/posts/golang-for-bioinformatics/

[samuell]

I'm really quite divided about Rust vs Mojo for bioinformatics in the future.

The syntax i Mojo really seems to shine a lot ... though I still wonder if the train has already left now that so much bioinfo work is already done in Rust.

[momojo]

I might have to look into mojo.

What's "alignment" in your context. In bioimaging it usually refers to aligning something to a reference atlas (like the Allen Reference Mouse Brain Atlas) or aligning two microscope channels (like the red channel and green channel)