Good tip "we suggest staying with uBlock Origin" but you still do need a Pi-Hole. It is that critical for a minimal setup to even open a page on any browser.
I wonder about what browser the Firefox CEO use. I have a guess.
A browser plugin doesn't help if you have apps with integrated ads.
(Btw, I know users who configure Android to use a publicly available ad-blocking DNS server instead of Pi-Hole)