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by plorg
39 days ago
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The same wiki article says there is a limit to the capacity of synthesis by UVB due to the quantity of reagent 7-dehydrocholesterol produced in the skin, but I don't know the math on what amount of exposure would be required to hit that limit - presumably it (or something like it) is covered in the article above. |
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https://en.wikipedia.org/wiki/7-Dehydrocholesterol
This study says "Findings include that small UV doses on a regular basis are more efficient for vitamin D synthesis than larger sub-erythemal doses", using a logarithmic model for blood calcifediol as a function of exposure.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8558903/
But it doesn't address colecalciferol production and storage. Fat stores colecalciferol, and I don't know of any way to measure that directly. I would guess that further UVB exposure linearly produces colecalciferol (with linear DNA damage, minus DNA repair with time), but the liver and kidneys logarithmically produce calcifediol and calcitriol. Just a guess. Still more questions :)