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by epistasis
50 days ago
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It was very obvious that it was a computational problem, all DNA analysis was highly computational then, as it is now. His guess was that ~500bp fragments would be enough to get a usable assembly. But the Human Genome Project's approach of reconstructing larger chunks first was also feasible, and produced an assembly too, with a heroic four weeks effort of a former game programmer who even built cluster software at the same time. |
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