[dragontamer]

This is a circuit with a switching regulator that is, presumably, stabilized with something on the order of a 10uH inductor + 22uF capacitor.

So from my perspective, increasing the capacitance from 22uF on that output line to 22.1uF with a 100nF cap will likely do jack diddly shit.

It is far more likely that, ex, the author of this post screwed up the regulator design. Ex: did the author mistakenly think that more capacitance is better-er and stick a 100uF cap there, blowing out the phase margin of the feedback of the switching regulator?

Was the inductor properly sized? Not just inductance but also saturation current and internal resistance?