[tempest_]

> Mental atrophy due to less learning/thinking, isolation, loss of meaning and purpose happens first.

Except early onset Alzheimers happens and it also happens to plenty of people for which none of those are true.

[iwalton3]

I mentioned this could be a possible falsification of the idea. It's also possible there are multiple causes and the modality I mentioned is a cause for some. I'm not sure. There are definitely cases where isolation contributes to cognitive decline.

[matwood]

Exactly. My mom lost her job because of early onset. She was very social, read tons of books, etc…. Now, I’m happy she at least still knows who am, but she can’t put a sentence together.

[josh-wrale]

Example: Claude Shannon