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by cmrx64 55 days ago
four figures these days. fits in your hand. nanopore is a revolution. https://nanoporetech.com/products/sequence/minion

there’s youtubers that have videos about doing this in a home wetlab. very achievable. some amateur soil biologists using this to try and sample microdiversity as the planet… humanifies.

3 comments

Ex-Nanopore employee here. One interesting thing we heard about internally was that OceanX[0] has one of our GridION[1] devices (slightly larger, and built-in compute) that they were using to track whales in the ocean by sequencing DNA found in seawater. Really cool.

[0] https://en.wikipedia.org/wiki/OceanX

[1] https://nanoporetech.com/products/sequence/gridion

huge if true had an episode about this recently https://www.youtube.com/watch?v=0HlLwG2xN_c
I have a mol bio home lab, and decided against it because while the devices themselves are reasonably priced, the flow cells are an expensive disposable.

I use Plasmidsaurus instead: Pay them $15/sample online, drop off the tubes in a styrophoam box labeled with a dinosaur in a nearby university building; get the results next morning. They use Oxford Nanopore, but are loading your sample along with many other samples to maximize flow cell use.

not suprised. the website seemed to indicate to me (a layman in this area) that it expired based on time, not use- so Seqiencing As A Service (ha!) makes financial sense for most people.
Do you have links to these youtubers? Sounds interesting
Not OP, but The Thought Emporium is a personal favourite. Their name belies the hands-on nature of their videos.

https://www.youtube.com/watch?v=F0_q-fD_lyU