[keepamovin]

I take pentoxyfylline (a synthetic substituted xanthine, caffeine is a natural substituted xanthine) occasionally as a nootropic and supplement for vascular health and anecdotally for me it has several nice caffeine like properties without the jitters/ long tail, sleep effects etc.

I find the listed side effects don’t happen for me besides occasional flush/blush. Which at my age is more like youthful vigor.

Caffeine is is 1,3,7-trimethylxanthine, pentoxyfylline is 3,7-dimethyl-1-(5-oxohexyl)xanthine.

Good effects are: sustained mental clarity, focus and energy with a smoother more stable baseline than caffeine’s bursty performance; good sleep, but strangely you can also stay up, if you prefer; feeling similar to “after exercise”. Half life is listed as under 1 hour, but beneficial effects can be felt for half a day after 400mg (a standard dose). So maybe there’s something like metabolite dynamics occurring here too.

This ends my erowid/hive style “trip/nootropic” report ;)

[ronjakoi]

You should start a xanthina where you serve various xanthinated beverages.

[CableNinja]

Coukd call it... xanzi-bar

[bookofjoe]

"Stand on Zanzibar" (1969 Hugo Award Winner) — John Brunner

Great book.

[quinncom]

Do you know how much it affects your deep sleep duration?

People who drink caffeine at night may claim to be able to sleep still, but they will find that deep sleep stages are shorter, which is significant because it may be the most important type of sleep.

[bot403]

I never slept as bad in my life as when I had a single can of coca cola at 8-9 pm and went to bed at 11-12pm

I did this for a while working nights until I caught on. The nights I didn't have a can were much better.

[keepamovin]

Seems to enhance sleep.

[qingcharles]

Pentoxyfylline is prescription in the USA?

[bookofjoe]

Yes

[keepamovin]

In other countries you can just buy