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by mapt
63 days ago
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This is a distinct claim. Caffeine can disrupt sleep even 48 hours later, a little bit; It is traditionally modelled with an elimination half-life of 5 hours, meaning 1/2 effect at 5 hours, 1/4 effect at 10 hours, 1/8 effect at 15 hours, an exponential decay curve. The claim being made is that due to cascading decay of a secondary metabolite that does a lot of the work producing the clinical effect, caffeine elimination is a much more linear, slow process that only reaches half effect at around 10 hours and 1/4 effect at 17 hours, 1/8 effect at 23 hours. |
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In your example, a 200 mg caffeine intake in the morning, least to 100mg at noon, 50mg at 5PM, 25mg at 10PM. Yes that means you still have 25mg of caffeine. But it's unlikely to have an outcome you can measure since it's below a minimum threshold.