| > Unfortunately, the Native Americans did not invent it quickly enough This is false. Most native Americans throughout both continents—especially those in Mesoamerica—were powerful civilisations in their own right with plenty of agricultural history. What finished many of them off was a lack of resistance to smallpox, which was brought over by the first explorers/colonists. |
We know about hantavirus in the southwestern US and Mexico but that seems unlikely to be the source based on its epidemiology. This is one of the most interesting scientific questions about North America, the possibility of a latent hemorrhagic virus that has heretofore not been isolated due to a few hundred years of dormancy.
Smallpox definitely added to the problem, especially in more northern parts of the Americas, but there is substantial evidence of brutal culling by a disease we can’t explain in the southern parts of North America.