Maybe. Depends on how good the substitute is. Demand for number crunching went up as costs went down, but nobody is training human "computers" anymore.
I don’t know that those people were exactly out of a job though, they didn’t do that job, but I find it hard to believe that any of the people solving orbital mechanics by hand wound up with nothing to do but twiddle their thumbs for the remainder of their lives. Similarly, I don’t know that there’s any realistic prospect, even if ai winds up writing all the software, that there wont also be incentive to have people that also understand it.