[rootusrootus]

You missed out on both of the weight suppression tricks, which really does suck. Appetite suppression (or reduction of food noise) is pretty useful, but GLP1s also tend to punish you mightily if you overeat. For me, even if I were hungry, overeating will make me hurt for hours. I could not gain weight on this even if I wanted to.

There are some difference, too, between the various drugs. I never tried ozempic, I went directly to tirzepatide (zepbound). And then to retatrutide. I will say that reta is in some ways the most interesting, because it has less appetite suppressing activity than tirzepatide (this is common, not just me), but it still cuts my stomach capacity quite a lot, and ramps up my metabolism. I had stalled at about 90 pounds down with tirzepatide, and reta immediately knocked off another 15. I track calories, and I had changed nothing. Felt more hungry, still lost more weight. Wild.

From one rando to another, I recommend trying tirzepatide. Or try semaglutide again but stacked with cagrilintide -- some people get pretty great results with that, similar to tirz.

[Teknoman117]

Yeah I might just have to go get it out of plan. Kaiser covers Ozempic, but none of the Tirzepatide based medications. (Edit: looks like that might have changed)

I am a big guy (6’4, 330 lbs), but I was amazed that Ozempic just seemed to do nothing. I was having the gastric side effects, but I could still eat 3000 calories a day if I cheated without feeling anything.

[gedy]

I highly recommend Zepbound, you might try it.

[AussieWog93]

Similar experience here with Tirzepatide. Overeating is punished swiftly and painfully.

If it works for you, look into getting one of the 15mg pens and counting clicks in order to get more doses per vial. I've been on the one pen for 3 months now and it's still got plenty of juice left.

[rootusrootus]

One of the quirks of buying brand name GLP1s in the US is that we don't get the dial-a-dose pens, every autopen is one-shot. Some people disassemble them to get multiple doses, but at that point you might as well get the cheaper brand name vials or go with compound or gray.

[phil21]

Lilly Direct sells zepbound in “single use” vials you make draws from. Very trivial to add bacteriostatic water to them and do some simple math to divide the dose. I have a few friends who do this.

You can also take apart the pens and do the same thing, but it’s a lot more involved and you’ll need to source some sterile reusable vials for it.

[Teknoman117]

When I was on Ozempic in the US (Bay Area), it was a dial-a-dose Ozempic branded pen. Came with 4-6 single use needles you’d screw onto the end before use, and discard into a sharps bin after.