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by bradleyy
94 days ago
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The actual study states in the summary that it's the cardiac protective improvement that reverses, not that you're worse off for having taken a GLP-1. So yeah, when you stop taking something that protects your heart and kidneys, it stops protecting... your heart and kidneys. There's an increasing body of work that indicates that long-term GLP use (initially higher doses for weight loss, then tapering down) retains the cardiac and kidney benefits and can actually lead to additional weight loss. |
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This is not at all obvious and still requires further study. Do the drugs themselves have heart- and kidney- protective effects, or are the heart and kidneys protected by maintaining a lower weight, or lower resting blood glucose, or lower inflammation, all of which are effects of the drug?