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Yes, totally agree that its not always applicable. But I think there is still lot of scope to offload some operation (e.g. magit operations like status, commit, streaming search result into minibuffer in ivy-mode). Having a dedicated protocol would of course be best (VSCode Remote works flawlessly for me).

>> What is the problem with mono repos?

If you use things like that depend on something like ivy/vertico/... find-file-in-project, projectile-find-file, ripgrep gets super slow (I think the reason is that they usually wait for entire result to be ready). LSP/Eglot gets slower. Similarly, will have to disable most of VC related stuff like highlight diff on fringe. Git will be inherently slower, so magit will hang your UI more often. Of course you can disable all these plugins and use vanilla emacs, but then if you remove enough of them you're likely going to be more productive with VSCode at that point.

Just to clarify this is experience with monorepo + tramp. Also not sure how much of its just plugins fault. Somwhat better if you use emacs locally where the monorepo is, however that often means using Emacs cli -- which usually means lose some of your keybindings.