[katdork]

as a trans woman, the clotting risk of estrogen proportional to levels is always cited to me by medical professionals when speaking about hrt, the risks, ...

i've always found it kind of weird, like being told taking estrogen will cause "increased chance of breast cancer"; yeah, if you grow breasts, you will have more breast cells, more cell division, more chance for errors, no? but that's (at least partially) why i'm doing the whole thing to begin with...? :p

and then they skimp on the doses...

if this were statistically significant to such a degree that it truly mattered, women would not live longer than men on average. i feel like people get lost in the sheer stats of it

[altairprime]

The underlying summary is interesting. In women (whether or not trans), the synthetics increase clotting risk more than the bioidenticals do; and, separately, oral dosing pathways increase clotting risk more than liver-bypassing pathways (patch, gel, etc). I'd like to see more women asked by their surgical team to switch to transdermal patches before surgery rather than asked to stop taking their hormones. Recovery will be worse with preventable hormone imbalances, after all.